Synthesis of Styryl-phenyl-ureas as Dual-targeted Inhibitors of PD-L1 and VEGFR-2
Programmed death-ligand 1 (PD-L1, cluster of differentiation 274, CD274, B7 homolog 1 or B7-H1) is a transmembrane protein that pla...
Actualizado: 05/07/2019
Synthesis of Arylpiperazines as Perspective Toxoplasma gondii Dihydrofolate Reductase Inhibitors
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii. Approximately one-third of the population worldwide is chronicall...
Actualizado: 05/07/2019
Synthesis of 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole Derivatives as Antiprotozoal Agents
Trypanosomatid and plasmodium parasites are producing a great deal of chronic diseases and affecting hundreds of millions people ma...
Actualizado: 05/07/2019
COMPUTER MODELING SERVICES FOR DRUG DISCOVERY
• Molecular docking and reverse molecular docking; • Pharmacophore modeling and reverse pharmacophore modeling; • Prediction of c...
Actualizado: 28/06/2023
RNA Targeted Library
RNA is important for the regulation of transcription, translational regulation, protein function and catalysis, which were classica...
Actualizado: 28/06/2023
Estrogen-related receptor gamma (ERRγ) Targeted Library
Estrogen-related receptor gamma (ERRγ) is involved in energy metabolism, mitochondrial functions, biogenesis and tissue repair. Dis...
Actualizado: 28/06/2023
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