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RNA Targeted Library

RNA is important for the regulation of transcription, translational regulation, protein function and catalysis, which were classically braked by protein function. RNA functions also include applications in the treatment of many diseases, including bacterial / viral infection and cancer. Secondary RNA structures such as double helices, hairpins, convexities, inner loop, stems - the structural basis for the development of therapeutic agents, which we took into account when developing our RNA target library (2542 compounds), which is a special screening library. It consists of compounds with putative RNA interaction activity. Compounds were selected according to Bayesian models using the most active matrix compounds. Separately, we collected a training set of target miRNA compounds taken from the PubChem database.
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Actualizado: 28/06/2023 11:09:48