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Synthesis of Arylpiperazines as Perspective Toxoplasma gondii Dihydrofolate Reductase Inhibitors

Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii. Approximately one-third of the population worldwide is chronicall...

Actualizado: 05/07/2019

Synthesis of Styryl-phenyl-ureas as Dual-targeted Inhibitors of PD-L1 and VEGFR-2

Programmed death-ligand 1 (PD-L1, cluster of differentiation 274, CD274, B7 homolog 1 or B7-H1) is a transmembrane protein that pla...

Actualizado: 05/07/2019

Synthesis of 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole Derivatives as Antiprotozoal Agents

Trypanosomatid and plasmodium parasites are producing a great deal of chronic diseases and affecting hundreds of millions people ma...

Actualizado: 05/07/2019

COMPUTER MODELING SERVICES FOR DRUG DISCOVERY

• Molecular docking and reverse molecular docking; • Pharmacophore modeling and reverse pharmacophore modeling; • Prediction of c...

EUR 1

Actualizado: 28/06/2023

RNA Targeted Library

RNA is important for the regulation of transcription, translational regulation, protein function and catalysis, which were classica...

Actualizado: 28/06/2023

Estrogen-related receptor gamma (ERRγ) Targeted Library

Estrogen-related receptor gamma (ERRγ) is involved in energy metabolism, mitochondrial functions, biogenesis and tissue repair. Dis...

Actualizado: 28/06/2023

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